Choosing the right audio interface can make guitar and vocal recording cleaner, easier, and more enjoyable. The best model depends on your input needs, monitoring preferences, computer or mobile setup, and budget.
We’ve selected 10 options ranging from compact beginner interfaces to more capable studio hubs, with attention to sound quality, connectivity, controls, software, and value.
Best 10 Audio Interface for Guitar and Vocals Picks for 2026
Reliable Starter Pick
Focusrite Scarlett Solo 3rd Gen
- One XLR mic input and one Hi-Z instrument input
- Air mode and 24-bit/192kHz recording
- Includes a useful software bundle
Best For: Solo guitarists and vocalists recording at home
Feature-Rich Budget Option
- Two XLR/TRS combo inputs with Hi-Z support
- 48V phantom power and zero-latency monitoring
- USB-C bus-powered 24-bit/192kHz recording
Best For: Portable two-input guitar and vocal setups
Modern Songwriter Choice
Focusrite Scarlett Solo 4th Gen
- 120dB dynamic range and 24-bit/192kHz support
- Improved Air modes for vocals and guitars
- Includes multiple recording and production tools
Best For: Songwriters wanting updated compact recording performance
Analog-Style Sound Pick
- Vintage mode emulates UA 610 preamp character
- 24-bit/192kHz recording with broad device support
- Includes LUNA and selected production software
Best For: Guitarists and vocalists seeking preamp color
Compact Starter Pick
- One combo mic/line input plus a separate instrument input
- 48 kHz recording with zero-latency monitoring
- Includes MPC Beats production software
Best For: Solo musicians, vocalists, podcasters, and portable home recording
Feature-Rich Upgrade
Focusrite Scarlett 2i2 4th Gen
- Two mic preamps and two Hi-Z instrument inputs
- 24-bit/192 kHz recording with 120 dB dynamic range
- Auto Gain, Clip Safe, and Air modes included
Best For: Musicians recording guitar and vocals together
Flexible Two-Input Value
- Two combo XLR/line/instrument inputs
- 48 kHz recording with direct zero-latency monitoring
- Includes balanced stereo outputs and MPC Beats
Best For: Simultaneous guitar-and-vocal recording and home production
Versatile Studio Hub
- Two mic preamps and two Hi-Z inputs
- Auto Gain, Clip Safe, and Air modes
- Four-in/four-out connectivity with MIDI
Best For: Expanding home studios recording vocals, guitars, and additional gear
Fender Tone Focus
- Fender-voiced instrument input
- Up to 75dB of clean mic gain
- Compact 2x2 USB-C design with loopback
Best For: Guitarists and vocalists wanting portable recording with Fender amp tones
Compact Creator Pick
- 24-bit/192kHz recording with 106dB dynamic range
- Dedicated guitar input and 48V phantom power
- Loopback routing for streaming and broadcasts
Best For: Beginners and creators recording guitar, vocals, and livestream audio
Reliable Starter Pick – Focusrite Scarlett Solo 3rd Gen
If you need an audio interface for guitar and vocals, the Scarlett Solo 3rd Gen offers a straightforward setup with one XLR microphone preamp and one Hi-Z instrument input. Its Air mode, Gain Halos, and 24-bit/192kHz recording make it well suited to home recording, songwriting, and podcasting.
Best For: Solo musicians recording guitar and vocals with a computer or compatible iPad.
Pros:
- Dedicated XLR mic preamp and Hi-Z instrument input for simultaneous guitar and vocal recording.
- Air mode can add clarity to acoustic instruments and vocals.
- Supports recording and mixing up to 24-bit/192kHz.
- Includes several recording programs, effects, instruments, and mastering tools.
Cons:
- Provides only one microphone preamp, limiting larger recording setups.
- The supplied details list a two-year warranty, while the product notes also reference three years, so warranty terms should be confirmed.
The Scarlett Solo 3rd Gen is a practical choice when you want dependable two-input recording without unnecessary complexity. It is especially appealing for a vocalist-guitarist who wants a familiar, compact interface and useful software included.
Feature-Rich Budget Option – PIYONE Q28 USB-C Interface
For an audio interface for guitar and vocals with flexible connectivity, the PIYONE Q28 combines two combo inputs, USB-C bus power, and 24-bit/192kHz recording. Its Hi-Z support, phantom power, direct monitoring, and 3.5mm headphone output make it adaptable for home and mobile recording.
Best For: Creators who want two combo inputs and portable USB-C recording at a budget-oriented price.
Pros:
- Two combo inputs accept microphones and guitar-level sources.
- 48V phantom power supports condenser microphones.
- Direct monitoring enables zero-latency tracking.
- USB-C handles data and bus power without a separate power supply.
Cons:
- The supplied operating-system details list Windows compatibility, so users on other systems should verify support.
- Its 0.74 kg weight is higher than some compact single-input interfaces.
The Q28 stands out for offering two flexible inputs and practical monitoring features in a portable package. It is a sensible option for guitar-and-vocal sessions when you value connection flexibility and USB-C convenience.
Modern Songwriter Choice – Focusrite Scarlett Solo 4th Gen
The Scarlett Solo 4th Gen is a strong audio interface for guitar and vocals when you want a compact setup with upgraded conversion performance. It pairs one XLR mic preamp with one Hi-Z instrument input, while its 120dB dynamic range and improved Air modes are designed to help performances sit clearly in a mix.
Best For: Songwriters seeking a current-generation interface for recording one microphone and one guitar or instrument.
Pros:
- 120dB dynamic range uses converters from Focusrite’s higher-end interface range.
- Improved Air modes add presence and harmonic drive to vocals and guitars.
- Supports 24-bit/192kHz recording and works with PC, Mac, and iPad.
- Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion.
Cons:
- Only one XLR microphone preamp is available.
- The product details list one audio input despite describing separate mic and instrument connections, so input configuration should be checked before purchase.
Compared with the previous generation, this Solo emphasizes improved dynamic range and more developed Air processing. It is a good fit for a guitarist-vocalist who wants a compact, modern Focusrite workflow and room to shape the sound during recording.
Analog-Style Sound Pick – Universal Audio Volt 1
For an audio interface for guitar and vocals with a more characterful recording option, the Universal Audio Volt 1 adds a Vintage mode modeled after UA’s classic 610 preamps. It records at up to 24-bit/192kHz and supports Mac, Windows, iPad, and iPhone workflows, making it useful for studio and mobile sessions.
Best For: Musicians who want UA-style preamp character and access to LUNA and included production software.
Pros:
- Vintage mode is designed to provide the rich sound of classic 610 preamps.
- Supports up to 24-bit/192kHz recording and mixing.
- Compatible with computers and selected iPad and iPhone recording setups.
- Includes access to LUNA and a selection of software instruments and plug-ins.
Cons:
- The supplied notes specify that mobile use may require an external power supply and Apple adapter.
- Only one microphone/instrument input channel is provided.
- The listed warranty is one year.
The Volt 1 is a compelling choice when recording tone matters as much as basic connectivity. Its Vintage mode and UA software ecosystem give it a distinct appeal for guitarists and vocalists who want an analog-inspired workflow in a compact interface.
Compact Starter Pick – M-Audio M-Track Solo
The M-Audio M-Track Solo is a compact, straightforward audio interface for guitar and vocals. Its combo input with phantom power handles microphones, while the separate line/instrument input accommodates guitar or another line-level source. USB connectivity, zero-latency monitoring, and included MPC Beats software make it useful for recording, podcasting, and streaming.
Best For: Solo musicians, vocalists, podcasters, and home users who need a portable two-channel interface.
Pros:
- Supports guitar, vocals, and line inputs through flexible connections.
- Crystal Preamp supports condenser microphones with phantom power.
- USB/Direct monitoring switch helps provide zero-latency monitoring.
- Includes MPC Beats and a USB cable.
Cons:
- Limited to a 48 kHz maximum sample rate.
- Only one combo XLR/line input is provided for microphone or line use.
- Uses USB Type-B connectivity rather than USB-C.
The M-Track Solo prioritizes simplicity and portability over expanded recording flexibility. It is a practical entry-level choice when you mainly need one microphone input plus a guitar or instrument connection.
Feature-Rich Upgrade – Focusrite Scarlett 2i2 4th Gen
The Focusrite Scarlett 2i2 4th Gen is a strong audio interface for guitar and vocals when recording quality and hands-on level control matter. It offers two mic preamps, two Hi-Z instrument inputs, 24-bit/192 kHz support, and a 120 dB dynamic range. Auto Gain, Clip Safe, and Air modes add useful tools for capturing and shaping performances.
Best For: Musicians who want two simultaneous inputs, higher-resolution recording, and helpful level-setting features.
Pros:
- Two mic preamps and two Hi-Z instrument inputs support guitar-and-vocal setups.
- 24-bit/192 kHz recording and a 120 dB dynamic range provide substantial technical headroom.
- Auto Gain and Clip Safe help manage recording levels.
- Air modes add presence and harmonic drive to vocals and guitars.
Cons:
- It is heavier than the M-Audio Solo at 1.7 pounds.
- The supplied notes specify USB connectivity but do not detail additional output formats.
- Its broader feature set may be more than beginners need for basic recording.
The Scarlett 2i2 is the most capable option here for musicians recording guitar and vocals together. Its higher sample-rate support and performance-focused features make it a compelling choice for users planning to build a more developed home setup.
Flexible Two-Input Value – M-Audio M-Track Duo
The M-Audio M-Track Duo is a practical audio interface for guitar and vocals when you want two combo inputs in a compact, affordable design. Both inputs accept XLR, line, or instrument signals and include phantom power, making it suitable for recording a microphone and guitar at the same time. Direct monitoring and included MPC Beats software add convenience for home recording and streaming.
Best For: Two-source recording, such as a vocalist and guitarist, podcasting, and basic home production.
Pros:
- Two combo XLR/line/instrument inputs support simultaneous guitar and vocal recording.
- Phantom power and Crystal Preamps accommodate condenser microphones.
- USB/Direct monitoring switch supports zero-latency monitoring.
- Includes balanced stereo outputs and MPC Beats software.
Cons:
- Maximum sample rate is 48 kHz.
- USB Type-B connectivity is less current than USB-C.
- Its two-channel design is not intended for larger multi-microphone sessions.
The M-Track Duo is a sensible value pick when two flexible inputs are more important than high sample-rate recording. It offers a straightforward way to capture guitar and vocals together without requiring a larger interface.
Versatile Studio Hub – Scarlett 4i4 4th Gen
If you need an audio interface for guitar and vocals with room to expand, the Focusrite Scarlett 4i4 4th Gen offers two mic preamps, two Hi-Z instrument inputs, four line inputs, four outputs, and MIDI I/O. Its Auto Gain, Clip Safe, and Air features also make recording easier for home-studio workflows.
Best For: Musicians recording vocals, guitars, and multiple additional instruments or hardware.
Pros:
- Two mic preamps and two Hi-Z inputs support simultaneous vocal and guitar recording.
- 120dB dynamic range and up to 24-bit/192kHz recording support detailed captures.
- Auto Gain, Clip Safe, and Air mode help simplify levels and add presence to vocals and guitars.
- Includes a broad software bundle with Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion.
Cons:
- Its larger I/O set may be more than a basic two-input setup requires.
- Requires USB-C power, though a USB-C to USB-A adapter is included.
The Scarlett 4i4 is a strong choice when your guitar-and-vocal setup may grow into a more capable studio rig. MIDI and extra line connections add useful flexibility beyond basic recording.
Fender Tone Focus – Quantum LT2 USB Interface
The Fender Quantum LT2 is a compact audio interface for guitar and vocals built around a 2×2 USB-C design. It combines a Fender-voiced instrument input with a high-gain mic preamp, low-latency drivers, and access to Fender amp and effects software.
Best For: Guitarists and vocalists who want a portable two-input setup with Fender tones.
Pros:
- Fender instrument input is voiced for full, dynamic guitar and bass recordings.
- MAX-HD mic preamp provides up to 75dB of clean gain for microphones.
- Compact 2×2 USB-C design includes balanced outputs and a high-power headphone amp.
- Fender Studio app provides access to Fender amp models and effects, with a six-month Fender Studio Pro trial included through registration.
Cons:
- Two-channel I/O offers less expansion than larger interfaces.
- The Fender amp and effects pack requires registration and app download.
For a straightforward guitar-and-vocal rig, the Quantum LT2 keeps the hardware compact while emphasizing Fender’s instrument voicing and software ecosystem. Loopback routing also adds flexibility for streaming and content creation.
Compact Creator Pick – MAONO PS22 Lite
The MAONO PS22 Lite is a compact audio interface for guitar and vocals aimed at beginners, streamers, and home recordists. It offers a dedicated instrument input, XLR microphone support with 48V phantom power, direct monitoring, and routing software for loopback setups.
Best For: Beginners and content creators building an affordable guitar, vocal, or streaming setup.
Pros:
- Supports 24-bit/192kHz recording with a stated 106dB dynamic range.
- Dedicated instrument input includes impedance adjustment for guitar use.
- Mic input offers up to 56dB of preamp gain and 48V phantom power for condenser microphones.
- Compact design works with Mac, Windows, and iPad, while ProStudio Routing Software adds loopback channels.
Cons:
- Its feature set is oriented toward compact two-input recording rather than larger studio expansion.
- Users may need to select the MAONO ASIO driver manually in compatible software.
The PS22 Lite is a practical entry point for recording guitar and vocals or combining music with livestream audio. Its direct monitoring, simple operating modes, and small footprint suit flexible desktop setups.
How We Picked the Best Audio Interface for Guitar and Vocals
We focused on interfaces that support the two most common home-recording sources: an electric or acoustic guitar and a microphone. Each pick was assessed for input configuration, preamp and converter specifications, direct monitoring, headphone connectivity, portability, software support, and overall ease of use.
We also included both one-input and two-input designs. A single-input model can be a smart choice for solo overdubbing, while two or more simultaneous inputs are better for recording guitar and vocals together, stereo sources, or multiple performers.
Quick Comparison
| Best For | Recommended Type | Why It Matters |
|---|---|---|
| Solo guitar or vocal recording | Compact 1-in/2-out interface | Saves space and keeps controls simple |
| Guitar and vocals at once | 2-in/2-out interface | Allows simultaneous microphone and instrument recording |
| Multiple microphones or instruments | 4-input interface | Provides room for overdubs, stereo recording, and collaboration |
| Streaming and content creation | Interface with simple monitoring controls | Makes live audio management easier |
Key Buying Factors for an Audio Interface for Guitar and Vocals
Inputs and Connection Types
Look for XLR microphone inputs with phantom power if you use a condenser microphone. A combo XLR/TRS input can accept either a microphone, line-level source, or guitar cable. For electric guitar, confirm that the interface includes an instrument or Hi-Z mode; this helps preserve the pickup’s tone and level.
Input Count and Recording Plans
If you record one source at a time, one microphone input may be sufficient. For simultaneous guitar and vocals, choose at least two independent inputs. Extra inputs are useful if you plan to add a second microphone, stereo keyboard, drum machine, or another musician.
Latency and Monitoring
Direct monitoring lets you hear the incoming signal with little or no computer delay. This is especially helpful when singing or playing through headphones. If you intend to use software amp effects while performing, also consider driver stability, buffer settings, and your computer’s performance.
Resolution, Outputs, and Compatibility
24-bit recording is standard for modern home studios, while higher sample-rate support can be useful for particular workflows but should not outweigh reliable drivers and good controls. Check USB compatibility, headphone output quality, balanced monitor outputs, and support for your operating system or iOS device.
Who Should Buy Which Audio Interface for Guitar and Vocals?
Beginners and solo creators: Choose a compact, straightforward interface with one or two inputs and direct monitoring. It will cover voiceover, songwriting, lessons, and basic guitar recording without unnecessary complexity.
Singers who play guitar: A two-input model is the most practical choice because it can capture a microphone and guitar simultaneously while leaving room for separate level control.
Producers and collaborators: Consider a four-input interface if you expect to record multiple sources, stereo instruments, or another performer. The extra connectivity can prevent an early upgrade.
Streamers and mobile creators: Prioritize simple monitoring, dependable USB operation, compact design, and compatibility with your preferred computer or mobile device. Before buying, verify whether any required adapters or cables are included.